Olfaction

Animal exhibit distinct behavior that dependent their internal states even for the same sensory input. Drosophila larva responds different to odors when starved compared with fed. This internal state dependent oflactory behavior is controled by a topdown feedback to antennal lobe circuit.

To achieve efficient coding of odor information in an array of nonlinear olfactory receptors, the odor-receptor sensitivity matrix must be sparse. This sparsity depends on the statistics of environmental odors. We used analytical calclation and extensive numerical simulation to study the optimal sensitivity matrix for recptors with and without spontaneous (background) activity.

We built a circuit model of the first olfactory information processing center of fruit fly, which incorporates key features of neuron-neuron interactions such as short-term plasticity and presynaptic inhibition.

Many animals perceive odorant molecules by collecting information from ensembles of olfactory neurons. Each neuron employs receptors …

In Drosophila, olfactory information received by olfactory receptor neurons (ORNs) is first processed by an incoherent feed forward …

Multineuronal imaging of the odor responses in C. elegans and decoding analysis revealed a distinct organization compared with insects and mamammlians.

Inhibitory response occurs throughout the nervous system, including the peripheral olfactory system. While odor-evoked excitation in …